europa    seventh

Stakeholder Consultation on the results of the G-TwYST feeding studies

and on general conclusions and recommendations


Written Consultation, 5 -23 Feb 2018

Stakeholder Workshop, 28-29 MARCH 2018, Hotel Seminarie Elzenveld, Lange Gasthuisstraat 25, 2000 Antwerpen, Belgium.



In the course of the European Commission funded research project G-TwYST (Genetically modified plants Two Year Safety Testing) 90-day, 1- and 2-year whole food/feed animal feeding studies were conducted with  GM maize NK603 in order to develop quality criteria and evaluate their scientific value for GMO risk assessment. Planning-stage issues relevant to these feeding studies were discussed in the workshop of December 2014 and in the written consultation of January 2015. The comments received on those two occasions were addressed when finalising the study plans. Comments and G-TwYST-team responses are available at https://www.g-twyst.eu/reports/workshop-documentys-planning-phase.

This consultation will provide an opportunity to review the results obtained and to discuss their interpretation.


The consultation has two subsequent steps.

  1. First, the draft results of the 90-day subchronic toxicity study with diets containing 11% and 33% GM maize NK603 will be made available for a written stakeholder consultation in early February 2018. The deadline for written comments on the results of this study is February 23.
  2. Second step would be a stakeholder workshop, organised on 28-29 March 2018 in Antwerp. This workshop will focus on the draft results of another 90-day study with 50% inclusion rate of GM maize NK603, as well as the one-year and the two-year studies. Also included in the scope would be proposed quality criteria for whole-food animal feeding studies, and preliminary conclusions on the scientific value of such studies for GMO risk assessment. An additional agenda item will be insights from an analysis of scientific controversies around animal feeding studies including the GMO case. Written comments, including interested parties not able to attend, are welcome, and should be submitted before 6 April. Please, note, due to the tight schedule of the final phase of the project, this will be a firm deadline.

The preliminary programme of the workshop can be downloaded here.


The aim of this consultation is to discuss the draft results and preliminary conclusions of the tasks described above.


To prepare for the consultation, documentation will be providedin advance for both the written consultation and the stakeholder meeting to registered parties. An electronic registration form is available here. Deadline for registration was March 14.

Non Disclosure Agreement

Since the documentation will contain data that will be used for publication in peer reviewed journals at a later stage along with draft interpretations and preliminary conclusions, we also require participants in the consultation to sign a Non Disclosure Agreement (NDA). The NDA can be downloaded from the G-TwYST website. Please fill in your name, affiliation, address and signature and send it to or to the address indicated on the NDA form.


Presentation of final results

The final results of G-TwYST will be presented in Bratislava, Slovakia, on April 16, 2018. This event will be open to all who are interested, including press. We will send a seperate invitation in February.

Latest news

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G-TwYST results published

13 February 2019

This week the paper  "Lack of adverse effects in subchronic and chronic toxicity/carcinogenicity studies on the glyphosate-resistant genetically modified maize NK603 in Wistar Han RCC rats" has been published in Archives of Toxicology. The open source paper is available online at https://doi.org/10.1007/s00204-019-02400-1.

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G-TwYST data available at CADIMA

13 February 2019

G-TwYST has  made accessible the detailed scientific information including raw data via the open access database CADIMA set up by the FP7 project GRACE.

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