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europa    seventh

G-TwYST is a Collaborative Project of the Seventh Framework Programme of the European Community for Research, Technological Development and Demonstration Activities. The project duration is from 21 April 2014 – 20 April 2018.

 

Work packages

The project consists of 7 work packages:

  1. Project coordination and management
  2. Feed production and plant analysis
  3. Feeing trials
  4. Biostatistics
  5. Scientific value and societal issues
  6. Central access database
  7. Stakeholder engagement, Ccommunication and dissemination

 

Project partners

  • Stiftung Tierärtzliche Hochschule Hannover, Germany, leader of work package 1 and work package 5.
  • Julius Kühn-Institut, Bundesforschungsinstitut für Kulturpflanzen, Germany, leader of work package 2 and work package 6.
  • Centre for Research in Agricultural Genomics, Spain, co-leader of work package 2.
  • Slovak Medical University, Slovakia, leader of work package 3.
  • Roger Alison Ltd., UK, involved in work package 3.
  • Stichting Dienst Landbouwkundig Onderzoek, Wageningen University and Research Centre, the Netherlands, leader of work package 4.
  • Universität Klagenfurt, Biotechnology Research Unit, Austria, leader of work package 7 and co-leader of work package 5.
  • LIS Consult, the Netherlands, co-leader of work package 7.

Read more about the project partners......

 

Advisory Board

G-TwYST has an Advisory Board that monitors the progress of the Project and provides an external objective assessment and recommendations where necessary. The members of the advisory board are:

  • Didier Breyer, Scientific Institute of Public Health, Service de Biosécurité et Biotechnologie, Direction Opérationnelle Expertise, Prestations de service et relations clients, Belgium.
  • Franck Foures, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Direction de l'évaluation des risques.
  • Kaja Kantorska, European Commission, Directorate General Health and Consumers.
  • Annette Pöting, Federal Institute for Risk Assessment, Unit Food Toxicology, Department Food Safety, Germany.
  • Kerstin Schmidt, BioMath GmbH, Applied Statistics and Informatics in Life Sciences, Germany.
  • Dieter Schrenk, Technical University Kaiserslautern, Department of food chemistry and environmental toxicology, Germany.

 

Organization

 

G-TwYST organization structure.jpg

 

 

 

 

 

 

 

Latest news

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1-year feeding study with MON810 on ARTE

In October 2016 ARTE broadcasted "OGM - Mensonges et vérités" (GMOs - Lies and truths) on French and German Television. In this 100 minutes long documentary Frédéric Castaignède sheds light on genetically modified crops, the impact on farmers, biodiversity and human health. We have selected and translated a fragment in which G-TwYST project leader Prof Pablo Steinberg presents the results of the 1-year feeding study with MON810 maize in the GRACE project.

 

The documentary provides a ‘snapshot’ of the GRACE final Conference which took place on November 9-10 2015 in Potsdam, Germany. We refer to videos on the GRACE Youtube channel  for a full account.

 

Paper published describing the statistical approach for equivalence testing in G-TwYST

An open access paper describing the statistical approach for equivalence testing in G-TwYST has now been published in Food and Chemical Toxicology. The method was tested on data from the GRACE project, as described in this paper. We will now progress by applying the method in the statistical analyses of the G-TwYST feeding trials, to be reported first in the statistical reports as project deliverables.

Highlights

  • An equivalence testing method is proposed to assess the safety of regulated products
  • We combine data from a current study with test and control, and historical studies with assumedly safe reference products
  • The method is illustrated with animal feeding studies using genetically modified and reference maize varieties
  • A high statistical power of the equivalence test is the basis for the equivalence criterion
  • Generalized fiducial inference is used to integrate uncertainties from the historical and the current data

 

van der Voet H, Goedhart PW, Schmidt K (2017). Equivalence testing using existing reference data:  an example with genetically modified and conventional crops in animal feeding studies. Food and Chemical Toxicology, 109: 472-485. https://doi.org/10.1016/j.fct.2017.09.044

G-TwYST Interim Report available

15 February 2017

 

The G-TwSYT team completed a publicly available Interim report with information about the progress that has been made in the first 1.5 years of the project. The report can be downloaded here.