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 In the context of the ongoing debate on the risk assessment of GM food/feed in Europe, it is crucial to put the findings of the 2-year feeding study in a perspective that also covers not only normative dimensions.


Normative dimensions regarding whole-food animal toxicity studies for GMO risk assessment will be identified and characterised. In a second step an analysis on how they relate to the scientific aspects will follow. The overall approach is to compare the controversy on animal toxicity studies in GMO risk assessment to (i) other science-policy conflicts related to animal toxicity studies in food safety, which will be elaborated as case studies, e.g. radiated food (historical case study), aspartame (food additive), EHEC contamination (food contamination) and (ii) to routine toxicity assessment practice.


The draft analytical framework for the comparative analysis and the selection of case studies will be discussed and refined in a mini workshop with external experts. The draft analysis and conclusions will be summarised in a journal manuscript to be discussed and revised based on a combined expert/stakeholder workshop.

In the course of the above-mentioned expert/stakeholder workshop, the results from the analysis of normative dimensions will be brought together and the role of normative dimensions for the justification of long-term studies will be discussed.

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Comments on statistical methods for safety assessment published

March 6, 2018


In safety assessments a large number of non-target effects  has to be analysed statistically. A recent paper published in the Journal of Agricultural and Food Chemistry advocates an approach which leads to over-optimistic conclusions. In a recent Correspondence to this journal the concerns about the misapplication of methodology are explained. See: Safety Assessments and Multiplicity Adjustment: Comments on a Recent Paper, available on the Journal of Agricultural and Food Chemistry website at http://pubs.acs.org/doi/abs/10.1021/acs.jafc.7b03686.

Registration for Final Conference open

1 March, 2018


On April 16, 2018 G-TwYST organises a conference on general conclusions and recommendations from three scientific projects: G-TwYST, GRACE and GMO90+. Registration for this conference is compulsory and can be done by completing the registration form at the G-TwYST website. Registration is open until April 6, 2018.

More information, including a preliminary programme, is available on the G-TwYST Final Conference webpage.